Anti -GRP94 Rabbit Primary Polyclonal Antibody for ResearchProduct Information
GRP94 rabbit polyclonal
|Protein full name|
94 kDa glucose-regulated protein, GRP-94, ERp99, Heat shock protein 90 kDa beta member 1, Polymorphic tumor rejection antigen 1, Tumor rejection antigen gp96, Hsp90b1, Grp94, Tra-1, Tra1
Recombinant protein corresponding to Mouse GRP94
P14625, P08113, Q66HD0
Human, Mouse, Rat
1: 500-1: 1000
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
Western blot analysis of GRP94 (GB111280) at dilution of 1: 1000
|Store at -20 ºC for one year. Avoid repeated freeze/ thaw cycles.|
|PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol.|
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Wuhan Servicebio Technology Co., Ltd. was founded in 2007, headquartered in Wuhan Optical Valley Biological City, is a high-tech enterprise specializing in providing technical services and scientific research products for life and health science research. With more than 1000 employees and more than 40 service centers in large and medium-sized cities across the country, it can provide support and service to scientists who explore the mysteries of life in an all-round way.
The company has strong scientific research and service strength, has antibody research and development and production center, ultra-micro pathology center, pathological detection center, SPF experimental animal center and other technical platforms, (the company also) has a complete set of experimental platforms, instruments and equipment for pathological immune detection and analysis, and mastered the technical core and patented technology, and independently developed and optimized a variety of experimental methods and processes, and developed a number of matching reagents and consumables. The company has a special R & D team to produce and verify antibodies. Laboratory consumables centrifugal tubes and suckers have formed large-scale production and can be automated packaged. We can provide experimental design, method optimization, Experimental operation, analysis and testing, reagent consumables and other omni-directional integrated scientific research and technical services for customers.
The experimental instruments have passed the system certification, not only the internal introduction of ISO9001 quality management system, but also through the European Union CE security certification and FCC certification, National High-tech Enterprise Certification and so on.
The company has more than 500 kinds of products, exported to Europe, the Middle East, Southeast Asia, Africa, America and other countries. All the products are well received by customers. The lab instruments and consumables independently R&D by Servicebio are widely used in more than 200 cities in China.